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| Cat.No | ACP16428 | Target Name | THSD4 |
|---|---|---|---|
| Target Synonyms | THSD4; UNQ9334/PRO34005; Thrombospondin type-1 domain-containing protein 4; A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6; ADAMTS-like protein 6; ADAMTSL-6 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZMP0 |
|---|
Uniprot Id
Q6ZMP0
Target Species
Human
Target Name
THSD4
Target Full Name
Thrombospondin type-1 domain-containing protein 4
Target Function
Promotes FBN1 matrix assembly. Attenuates TGFB signaling, possibly by accelerating the sequestration of large latent complexes of TGFB or active TGFB by FBN1 microfibril assembly, thereby negatively regulating the expression of TGFB regulatory targets, such as POSTN.
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Synonyms
THSD4; UNQ9334/PRO34005; Thrombospondin type-1 domain-containing protein 4; A disintegrin and metalloproteinase with thrombospondin motifs-like protein 6; ADAMTS-like protein 6; ADAMTSL-6
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