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| Cat.No | ACP08298 | Target Name | TOR1AIP1 |
|---|---|---|---|
| Target Synonyms | TOR1AIP1; LAP1; Torsin-1A-interacting protein 1; Lamin-associated protein 1B; LAP1B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5JTV8 |
|---|
Uniprot Id
Q5JTV8
Target Species
Human
Target Name
TOR1AIP1
Target Full Name
Torsin-1A-interacting protein 1
Target Function
Required for nuclear membrane integrity. Induces TOR1A and TOR1B ATPase activity and is required for their location on the nuclear membrane. Binds to A- and B-type lamins. Possible role in membrane attachment and assembly of the nuclear lamina.
Target Involvement
Limb-girdle muscular dystrophy 2Y (LGMD2Y)
Target Subcellular Location
Nucleus inner membrane; Single-pass membrane protein.
Target Protein Families
TOR1AIP family
Target Tissue Specificity
Expressed in muscle, liver and kidney.
Target Synonyms
TOR1AIP1; LAP1; Torsin-1A-interacting protein 1; Lamin-associated protein 1B; LAP1B
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