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Recombinant Human Trafficking kinesin-binding protein 1 (TRAK1), Truncated

ACP10076

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10076 Target NameTRAK1
Target SynonymsTRAK1; KIAA1042; OIP106; Trafficking kinesin-binding protein 1; 106 kDa O-GlcNAc transferase-interacting protein; Protein MiltonFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9UPV9
Background Information
  • Uniprot Id

    Q9UPV9

  • Target Species

    Human

  • Target Name

    TRAK1

  • Target Full Name

    Trafficking kinesin-binding protein 1

  • Target Function

    Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes. TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria.

  • Target Subcellular Location

    Cytoplasm. Nucleus. Mitochondrion. Early endosome. Endosome. Mitochondrion membrane. Cytoplasm, cell cortex.

  • Target Tissue Specificity

    High expression in spinal cord and moderate expression in all other tissues and specific brain regions examined. Expressed in all cell lines examined.

  • Target Synonyms

    TRAK1; KIAA1042; OIP106; Trafficking kinesin-binding protein 1; 106 kDa O-GlcNAc transferase-interacting protein; Protein Milton

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