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Recombinant Human Transcription factor HES-5 (HES5)

ACP16763

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16763 Target NameHES5
Target Synonyms5; HES 5; hes family bHLH transcription factor 5; Hes5; HES5 protein; HES5_HUMAN; MGI:104876; Transcription factor HES-5, bHLHb38; Class B basic helix-loop-helix protein 38; Hairy and enhancer of split 5; Hairy/Enhancer of spli, Drosophila, homolog ofFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-166
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5TA89
Background Information
  • Uniprot Id

    Q5TA89

  • Target Species

    Human

  • Target Name

    HES5

  • Target Full Name

    Transcription factor HES-5

  • Target Function

    Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Expressed in fetal heart and brain tumors.

  • Target Synonyms

    bHLHb38; Class B basic helix-loop-helix protein 38; Hairy and enhancer of split 5; Hairy/Enhancer of spli, Drosophila, homolog of, 5; HES 5; hes family bHLH transcription factor 5; Hes5; HES5 protein; HES5_HUMAN; MGI:104876; Transcription factor HES-5

  • Target Background

    This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.

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