Recombinant Human Transmembrane and TPR repeat-containing protein 3 (TMTC3), Truncated

ACP06072

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Specifications

Cat.No	ACP06072	Target Name	TMTC3
Target Synonyms	TMTC3; Protein O-mannosyl-transferase TMTC3; EC 2.4.1.109; Protein SMILE; Transmembrane and TPR repeat-containing protein 3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q6ZXV5

Background Information

Uniprot Id

Q6ZXV5
Target Species

Human
Target Name

TMTC3
Target Full Name

Protein O-mannosyl-transferase TMTC3
Target Function

Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl-transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O-mannosyl-transferase on other proteins such as PDIA3. Involved in the positive regulation of proteasomal protein degradation in the endoplasmic reticulum (ER), and the control of ER stress response.
Target Involvement

Lissencephaly 8 (LIS8)
Target Subcellular Location

Membrane; Multi-pass membrane protein. Endoplasmic reticulum.
Target Protein Families

TMTC family
Target Synonyms

TMTC3; Protein O-mannosyl-transferase TMTC3; EC 2.4.1.109; Protein SMILE; Transmembrane and TPR repeat-containing protein 3

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Recombinant Human Transmembrane and TPR repeat-containing protein 3 (TMTC3), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Transmembrane and TPR repeat-containing protein 3 (TMTC3), Truncated Now

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