Recombinant Human Transmembrane emp24 domain-containing protein 1 (TMED1), Truncated

Uniprot Id

Q13445

Target Species

Human

Target Name

TMED1

Target Full Name

Transmembrane emp24 domain-containing protein 1

Target Function

Potential role in vesicular protein trafficking, mainly in the early secretory pathway. May act as a cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and may be involved in vesicle coat formation at the cytoplasmic side.

Target Subcellular Location

Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein.

Target Protein Families

EMP24/GP25L family

Target Tissue Specificity

Widely expressed.

Target Synonyms

IL1RL1 binding protein; IL1RL1L; IL1RL1LG; Interleukin-1 receptor-like 1 ligand; Interleukin1 receptor like 1 ligand; MGC1270; p24 family protein gamma 1; p24gamma1; Putative T1/ST2 receptor binding protein; Putative T1/ST2 receptor-binding protein; ST2L; T1/ST2 receptor binding protein; TMED 1; Tmed1; TMED1_HUMAN; Tp24; Transmembrane emp24 domain containing 1; Transmembrane emp24 domain containing protein 1; Transmembrane emp24 domain-containing protein 1; Transmembrane emp24 protein transport domain containing 1; Transmembrane p24 trafficking protein 1

Target Background

This gene belongs to the TMED (transmembrane emp24 domain-containing) protein family, which is involved in the vesicular trafficking of proteins. The protein encoded by this gene was identified by its interaction with interleukin 1 receptor-like 1 (IL1RL1) and may play a role in innate immunity. This protein lacks any similarity to other interleukin 1 ligands. Alternative splicing results in multiple transcript variants of this gene.