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Recombinant Human tRNA wybutosine-synthesizing protein 5 (TYW5)

ACP22050

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22050 Target NameTYW5
Target SynonymsTYW5; C2orf60; tRNA wybutosine-synthesizing protein 5; hTYW5; EC 1.14.11.42; tRNA(Phe; 7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylaseFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-315
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDA2RUC4
Background Information
  • Uniprot Id

    A2RUC4

  • Target Species

    Human

  • Target Name

    TYW5

  • Target Full Name

    tRNA wybutosine-synthesizing protein 5

  • Target Function

    tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.

  • Target Protein Families

    TYW5 family

  • Target Synonyms

    TYW5; C2orf60; tRNA wybutosine-synthesizing protein 5; hTYW5; EC 1.14.11.42; tRNA(Phe; 7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase

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