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| Cat.No | ACP17274 | Target Name | TNFAIP8L3 |
|---|---|---|---|
| Target Synonyms | TNFAIP8L3; TIPE3; Tumor necrosis factor alpha-induced protein 8-like protein 3; TNF alpha-induced protein 8-like protein 3; TNFAIP8-like protein 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-292 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5GJ75 |
|---|
Uniprot Id
Q5GJ75
Target Species
Human
Target Name
TNFAIP8L3
Target Full Name
Tumor necrosis factor alpha-induced protein 8-like protein 3
Target Function
Acts as a lipid transfer protein. Preferentially captures and shuttles two lipid second messengers, i.e., phosphatidylinositol 4,5- bisphosphate and phosphatidylinositol 3,4,5-trisphosphate and increases their levels in the plasma membrane. Additionally, may also function as a lipid-presenting protein to enhance the activity of the PI3K-AKT and MEK-ERK pathways. May act as a regulator of tumorigenesis through its activation of phospholipid signaling.
Target Subcellular Location
Cytoplasm. Cell membrane.
Target Protein Families
TNFAIP8 family
Target Tissue Specificity
Widely expressed (at protein level). Highly expressed in most carcinoma cell lines.
Target Synonyms
TNFAIP8L3; TIPE3; Tumor necrosis factor alpha-induced protein 8-like protein 3; TNF alpha-induced protein 8-like protein 3; TNFAIP8-like protein 3
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