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| Cat.No | ACP15194 | Target Name | GID4 |
|---|---|---|---|
| Target Synonyms | GID4; C17orf39; VID24; Glucose-induced degradation protein 4 homolog; Vacuolar import and degradation protein 24 homolog | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-300 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IVV7 |
|---|
Uniprot Id
Q8IVV7
Target Species
Human
Target Name
GID4
Target Full Name
Glucose-induced degradation protein 4 homolog
Target Function
Substrate-recognition subunit of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1 (Probable). Binds proteins and peptides with a Pro/N-degron consisting of an unmodified N-terminal Pro followed by a small residue, and has the highest affinity for the peptide Pro-Gly-Leu-Trp. Binds peptides with an N-terminal sequence of the type Pro-[Ala,Gly]-[Leu,Met,Gln,Ser,Tyr]-[Glu,Gly,His,Ser,Val,Trp,Tyr]. Does not bind peptides with an acetylated N-terminal Pro residue
Target Protein Families
GID4/VID24 family
Target Synonyms
GID4; C17orf39; VID24; Glucose-induced degradation protein 4 homolog; Vacuolar import and degradation protein 24 homolog
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