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| Cat.No | ACP16833 | Target Name | SPOUT1 |
|---|---|---|---|
| Target Synonyms | SPOUT1; C9orf114Putative methyltransferase C9orf114; EC 2.1.1.-; Centromere protein 32; CENP-32; Kinetochore-associated protein; SPOUT domain-containing methyltransferase 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-376 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5T280 |
|---|
Uniprot Id
Q5T280
Target Species
Human
Target Name
SPOUT1
Target Full Name
Putative methyltransferase C9orf114
Target Function
Required for association of the centrosomes with the poles of the bipolar mitotic spindle during metaphase. Also involved in chromosome alignment. May promote centrosome maturation probably by recruiting A-kinase anchor protein AKAP9 to centrosomes in early mitosis. Binds specifically to miRNA MIR145 hairpin, regulates MIR145 expression at a postranscriptional level.
Target Subcellular Location
Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Target Protein Families
Class IV-like SAM-binding methyltransferase superfamily
Target Synonyms
SPOUT1; C9orf114Putative methyltransferase C9orf114; EC 2.1.1.-; Centromere protein 32; CENP-32; Kinetochore-associated protein; SPOUT domain-containing methyltransferase 1
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