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| Cat.No | ACP17746 | Target Name | SPIDR |
|---|---|---|---|
| Target Synonyms | SPIDR; KIAA0146; DNA repair-scaffolding protein; Scaffolding protein involved in DNA repair | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14159 |
|---|
Uniprot Id
Q14159
Target Species
Human
Target Name
SPIDR
Target Full Name
DNA repair-scaffolding protein
Target Function
Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity.
Target Subcellular Location
Nucleus. Note=Together with BLM, is redistributed in discrete nuclear DNA damage-induced foci following hydroxyurea (HU) or camptothecin (CPT) treatment.
Target Synonyms
SPIDR; KIAA0146; DNA repair-scaffolding protein; Scaffolding protein involved in DNA repair
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