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| Cat.No | ACP05771 | Target Name | KIAA1549 |
|---|---|---|---|
| Target Synonyms | KIAA1549; UPF0606 protein KIAA1549 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9HCM3 |
|---|
Uniprot Id
Q9HCM3
Target Species
Human
Target Name
KIAA1549
Target Full Name
UPF0606 protein KIAA1549
Target Function
May play a role in photoreceptor function.
Target Involvement
A chromosomal aberration involving KIAA1549 is found in pilocytic astrocytoma. A tandem duplication of 2 Mb at 7q34 leads to the expression of a KIAA1549-BRAF fusion protein with a constitutive kinase activity and inducing cell transformation.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell projection, cilium.
Target Protein Families
UPF0606 family
Target Tissue Specificity
[Isoform 1]: Expression is low to moderate in retina and tissues, such as heart and kidney, and is predominantly expressed in brain.; [Isoform 4]: Abundantly expressed in the retina, compared with only minimal expression in brain and other tissues.
Target Synonyms
KIAA1549; UPF0606 protein KIAA1549
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