Recombinant Human Uridine-cytidine kinase-like 1 (UCKL1)

Uniprot Id

Q9NWZ5

Target Species

Human

Target Name

UCKL1

Target Full Name

Uridine-cytidine kinase-like 1

Target Function

May contribute to UTP accumulation needed for blast transformation and proliferation.

Target Subcellular Location

Cytoplasm. Nucleus. Note=EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.

Target Protein Families

Uridine kinase family

Target Tissue Specificity

Ubiquitous.

Target Synonyms

F538; UCK 1L; UCK1 like; UCK1L; UCKL 1; UCKL1; UCKL1_HUMAN; Uridine cytidine kinase 1 like 1; Uridine kinase like 1; Uridine-cytidine kinase-like 1; Uridine/cytidine kinase like 1; URKL 1; URKL1

Target Background

The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants.