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| Cat.No | ACP00980 | Target Name | UCN2 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 72-112aa | Mol Weight | 17.4 kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96RP3 |
|---|
Uniprot Id
Q96RP3
Target Species
Human
Target Name
UCN2
Target Full Name
Urocortin-2
Target Function
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Target Subcellular Location
Secreted.
Target Protein Families
Sauvagine/corticotropin-releasing factor/urotensin I family
Target Research Area
Cardiovascular
Target Synonyms
SRP; Stresscopin related peptide; Stresscopin-related peptide; Ucn II; Ucn2; UCN2_HUMAN; UCNI; UCNII; UR; Urocortin II; Urocortin related peptide; Urocortin-2; Urocortin-related peptide; URP
Target Background
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.
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