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| Cat.No | ACP04061 | Target Name | MON1A |
|---|---|---|---|
| Target Synonyms | FLJ97088; MGC13272; MON1 homolog A; MON1A; MON1A_HUMAN; SAND1; Vacuolar fusion protein MON1 homolog A | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 205-555aa |
| Mol Weight | 56.2kDa | Protein Length | Partial |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86VX9 |
|---|
Uniprot Id
Q86VX9
Target Species
Human
Target Name
MON1A
Target Full Name
Vacuolar fusion protein MON1 homolog A
Target Function
Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form.
Target Protein Families
MON1/SAND family
Target Research Area
Signal Transduction
Target Synonyms
FLJ97088; MGC13272; MON1 homolog A; MON1A; MON1A_HUMAN; SAND1; Vacuolar fusion protein MON1 homolog A
Target Background
Enables guanyl-nucleotide exchange factor activity. Predicted to be involved in protein secretion. Predicted to act upstream of or within cellular iron ion homeostasis and protein transport. Part of Mon1-Ccz1 complex.
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