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Recombinant Human Vacuolar protein sorting-associated protein 52 homolog (VPS52)

ACP13133

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP13133 Target NameVPS52
Target SynonymsVPS52; SACM2LVacuolar protein sorting-associated protein 52 homolog; SAC2 suppressor of actin mutations 2-like proteinFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range2-723
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8N1B4
Background Information
  • Uniprot Id

    Q8N1B4

  • Target Species

    Human

  • Target Name

    VPS52

  • Target Full Name

    Vacuolar protein sorting-associated protein 52 homolog

  • Target Function

    Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.

  • Target Subcellular Location

    Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome.

  • Target Protein Families

    VPS52 family

  • Target Synonyms

    VPS52; SACM2LVacuolar protein sorting-associated protein 52 homolog; SAC2 suppressor of actin mutations 2-like protein

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