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Recombinant Human Vacuolar protein sorting-associated protein 53 homolog (VPS53)

ACP16812

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Specifications

Cat.No	ACP16812	Target Name	VPS53
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-699	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q5VIR6?

Background Information

Uniprot Id

Q5VIR6
Target Species

Human
Target Name

VPS53
Target Full Name

Vacuolar protein sorting-associated protein 53 homolog
Target Function

Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
Target Involvement

Pontocerebellar hypoplasia 2E (PCH2E)
Target Subcellular Location

Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane; Peripheral membrane protein. Recycling endosome.
Target Protein Families

VPS53 family
Target Synonyms

FLJ10979; FLJ41112; FLJ61757; HCCS1; hVps53L; MGC39512; pp13624; Vacuolar protein sorting 53 (yeast); Vacuolar protein sorting 53; Vacuolar protein sorting 53 homolog (S. cerevisiae); Vacuolar protein sorting-associated protein 53 homolog; VPS53; VPS53_HUMAN

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Recombinant Human Vacuolar protein sorting-associated protein 53 homolog (VPS53)

Specifications

Immunogen Information

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