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| Cat.No | ACP19676 | Target Name | VASN |
|---|---|---|---|
| Target Synonyms | 2610528G05Rik; PRO1282; PRO357; Protein slit-like 2; Slit like 2; Slitl2; UNQ314; Vasn; VASN_HUMAN; Vasorin | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6EMK4 |
|---|
Uniprot Id
Q6EMK4
Target Species
Human
Target Name
VASN
Target Full Name
Vasorin
Target Function
May act as an inhibitor of TGF-beta signaling.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Secreted.
Target Tissue Specificity
Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending ao
Target Synonyms
2610528G05Rik; PRO1282; PRO357; Protein slit-like 2; Slit like 2; Slitl2; UNQ314; Vasn; VASN_HUMAN; Vasorin
Target Background
Enables transforming growth factor beta binding activity. Involved in negative regulation of epithelial to mesenchymal transition and negative regulation of transforming growth factor beta receptor signaling pathway. Located in cell surface and extracellular exosome.
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