Recombinant Human Vesicle-associated membrane protein 3 (VAMP3), Truncated

Uniprot Id

Q15836

Target Species

Human

Target Name

VAMP3

Target Full Name

Vesicle-associated membrane protein 3

Target Function

SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

Target Subcellular Location

Membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.

Target Protein Families

Synaptobrevin family

Target Synonyms

CEB; Cellubrevin; Synaptobrevin 3; Synaptobrevin-3; VAMP 3; VAMP-3; VAMP3; VAMP3_HUMAN; Vesicle associated membrane protein 3; Vesicle-associated membrane protein 3

Target Background

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.