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Recombinant Human Vesicle-associated membrane protein-associated protein B/C (VAPB), Truncated

ACP06308

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Specifications

Cat.No	ACP06308	Target Name	VAPB
Target Synonyms	VAPB; UNQ484/PRO983; Vesicle-associated membrane protein-associated protein B/C; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAP-B/VAP-C	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O95292

Background Information

Uniprot Id

O95292
Target Species

Human
Target Name

VAPB
Target Full Name

Vesicle-associated membrane protein-associated protein B/C
Target Function

Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.
Target Involvement

Amyotrophic lateral sclerosis 8 (ALS8); Spinal muscular atrophy, proximal, adult, autosomal dominant (SMAPAD)
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type IV membrane protein.
Target Protein Families

VAMP-associated protein (VAP) (TC 9.B.17) family
Target Tissue Specificity

Ubiquitous. Isoform 1 predominates.
Target Synonyms

VAPB; UNQ484/PRO983; Vesicle-associated membrane protein-associated protein B/C; VAMP-B/VAMP-C; VAMP-associated protein B/C; VAP-B/VAP-C
Target Background

The protein encoded by this gene is a type IV membrane protein found in plasma and intracellular vesicle membranes. The encoded protein is found as a homodimer and as a heterodimer with VAPA. This protein also can interact with VAMP1 and VAMP2 and may be involved in vesicle trafficking.

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Recombinant Human Vesicle-associated membrane protein-associated protein B/C (VAPB), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Vesicle-associated membrane protein-associated protein B/C (VAPB), Truncated Now

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