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| Cat.No | ACP10876 | Target Name | WSB2 |
|---|---|---|---|
| Target Synonyms | WSB2; WD repeat and SOCS box-containing protein 2; WSB-2; CS box-containing WD protein | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-404 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NYS7 |
|---|
Uniprot Id
Q9NYS7
Target Species
Human
Target Name
WSB2
Target Full Name
WD repeat and SOCS box-containing protein 2
Target Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Target Synonyms
WSB2; WD repeat and SOCS box-containing protein 2; WSB-2; CS box-containing WD protein
Target Background
This gene encodes a member of the WD-protein subfamily. The encoded protein contains five WD-repeats spanning most of the protein and an SOCS box in the C-terminus. The SOCS box may act as a bridge between specific substrate-binding domains and E3 ubiquitin protein ligases. Three transcript variants encoding different isoforms have been found for this gene.
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