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Recombinant Human Y-box-binding protein 2 (YBX2)

ACP09510

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP09510 Target NameYBX2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-364Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9Y2T7
Background Information
  • Uniprot Id

    Q9Y2T7

  • Target Species

    Human

  • Target Name

    YBX2

  • Target Full Name

    Y-box-binding protein 2

  • Target Function

    Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Tissue Specificity

    Expressed in oocytes and testicular germ cells in the stage of spermatogonia to spermatocyte. Also observed placental trophoblasts, as well as in vascular smooth muscle cells in the pulmonary artery, myocardium, and skeletal muscle. Undetectable in epithe

  • Target Synonyms

    Contrin; CSDA 3; CSDA3; Dbpc; DNA binding protein C; DNA-binding protein C; FRGY2 homolog; Germ cell specific Y box binding protein; Germ cell-specific Y-box-binding protein; MGC118270; MGC45104; MSY 2; MSY2; MSY2 homolog; OTTMUSP00000006276; RGD1305068; Y box binding protein 2; Y-box-binding protein 2; YBOX2_HUMAN; YBX 2; YBX2

  • Target Background

    This gene encodes a nucleic acid binding protein which is highly expressed in germ cells. The encoded protein binds to a Y-box element in the promoters of certain genes but also binds to mRNA transcribed from these genes. Pseudogenes for this gene are located on chromosome 10 and 15.

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