Home Products Recombinant Human Y+L amino acid transporter 2 (SLC7A6), Truncated

Recombinant Human Y+L amino acid transporter 2 (SLC7A6), Truncated

ACP05864

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Specifications

Cat.No	ACP05864	Target Name	SLC7A6
Target Synonyms	SLC7A6; KIAA0245; Y+L amino acid transporter 2; Cationic amino acid transporter; y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q92536

Background Information

Uniprot Id

Q92536
Target Species

Human
Target Name

SLC7A6
Target Full Name

Y+L amino acid transporter 2
Target Function

Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
Target Subcellular Location

Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families

Amino acid-polyamine-organocation (APC) superfamily, L-type amino acid transporter (LAT) (TC 2.A.3.8) family
Target Tissue Specificity

Expressed in normal fibroblasts and those from LPI patients. Also expressed in HUVECs, monocytes, RPE cells, and various carcinoma cell lines.
Target Synonyms

SLC7A6; KIAA0245; Y+L amino acid transporter 2; Cationic amino acid transporter; y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2

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Recombinant Human Y+L amino acid transporter 2 (SLC7A6), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Y+L amino acid transporter 2 (SLC7A6), Truncated Now

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