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| Cat.No | ACP10637 | Target Name | YY1AP1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-796 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H869 |
|---|
Uniprot Id
Q9H869
Target Species
Human
Target Name
YY1AP1
Target Full Name
YY1-associated protein 1
Target Function
Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation.
Target Involvement
Grange syndrome (GRNG)
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus.
Target Tissue Specificity
Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
Target Synonyms
FLJ10875; FLJ13914; GRNG; HCCA1; HCCA2; Hepatocellular carcinoma susceptibility protein; Hepatocellular carcinoma-associated protein 2; OTTHUMP00000033475; OTTHUMP00000033476; OTTHUMP00000200831; OTTHUMP00000200832; OTTHUMP00000200833; OTTHUMP00000200836; YAP; YY1-associated protein 1; YY1AP; YY1AP1; YYAP1_HUMAN
Target Background
Predicted to enable transcription coregulator activity. Involved in cell differentiation; cell population proliferation; and regulation of cell cycle. Located in fibrillar center and nucleoplasm. Colocalizes with Ino80 complex.
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