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| Cat.No | ACP10343 | Target Name | ZCCHC4 |
|---|---|---|---|
| Target Synonyms | CCHC domain containing 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-513 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H5U6 |
|---|
Uniprot Id
Q9H5U6
Target Species
Human
Target Name
ZCCHC4
Target Full Name
rRNA N(6)-adenosine-methyltransferase ZCCHC4
Target Function
rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA. N6-methylation of adenine(4220) in 28S rRNA is required for translation.
Target Subcellular Location
Nucleus, nucleolus. Cytoplasm.
Target Synonyms
4930449I23Rik; DHHC domain containing zinc finger protein; HSPC052; MGC21108; OTTMUSP00000027189; zcchc4; ZCHC4_HUMAN; ZGRF4; Zinc finger CCHC domain containing protein 4; Zinc finger CCHC domain-containing protein 4; Zinc finger CCHC type containing 4; Zinc finger GRF type containing 4; Zinc finger, CCHC domain containing 4
Target Background
Enables S-adenosyl-L-methionine binding activity; rRNA (adenine-N6-)-methyltransferase activity; and zinc ion binding activity. Involved in positive regulation of translation and rRNA methylation. Located in cytoplasm and nucleolus.
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