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Recombinant Human Zinc finger E-box-binding homeobox 2 (ZEB2), Truncated

ACP21341

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Specifications

Cat.No	ACP21341	Target Name	ZEB2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O60315

Background Information

Uniprot Id

O60315
Target Species

Human
Target Name

ZEB2
Target Full Name

Zinc finger E-box-binding homeobox 2
Target Function

Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin. Represses expression of MEOX2.
Target Involvement

Mowat-Wilson syndrome (MOWS)
Target Subcellular Location

Nucleus. Chromosome.
Target Protein Families

Delta-EF1/ZFH-1 C2H2-type zinc-finger family
Target Synonyms

FLJ42816; HSPC082; KIAA0569; SIP 1; SIP1; Smad Interacting Protein 1; Smad-interacting protein 1; SMADIP 1; SMADIP1; ZEB 2; Zeb2; ZEB2_HUMAN; Zfhx1b; ZFHX1B protein; Zfx1b; Zinc finger E box binding protein 2; Zinc finger E-box-binding homeobox 2; Zinc finger homeobox 1b; zinc finger homeobox protein 1; Zinc finger homeobox protein 1b
Target Background

The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.

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Recombinant Human Zinc finger E-box-binding homeobox 2 (ZEB2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Zinc finger E-box-binding homeobox 2 (ZEB2), Truncated Now

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