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| Cat.No | ACP18649 | Target Name | ZNF750 |
|---|---|---|---|
| Target Synonyms | ZNF750; Zinc finger protein 750 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-723 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q32MQ0 |
|---|
Uniprot Id
Q32MQ0
Target Species
Human
Target Name
ZNF750
Target Full Name
Zinc finger protein 750
Target Function
Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression.
Target Involvement
Seborrhea-like dermatitis with psoriasiform elements (SLDP)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in the skin, prostate, lung, placenta and thymus, and at low level in T-cells. Not expressed in peripheral blood leukocytes, pancreas and brain. Clearly expressed in primary keratinocytes but not in fibroblasts.
Target Synonyms
ZNF750; Zinc finger protein 750
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