Recombinant Human Zymogen granule protein 16 homolog B (ZG16B)

Amino acids 53-208 form the expressed segment for recombinant Human ZG16B. The calculated molecular weight for this ZG16B protein is 21.2 kDa. This protein is generated in a e.coli-based system. Fusion of the N-terminal 6xHis tag into the ZG16B encoding gene fragment was conducted, allowing for easier detection and purification of the ZG16B protein in subsequent stages.Human zymogen granule protein 16 homolog B (ZG16B) is primarily involved in endoplasmic reticulum-associated protein degradation (ERAD). Its main function centers around recognizing and guiding misfolded proteins for degradation, contributing to cellular quality control. In the realm of cellular and molecular research, the study of ZG16B offers valuable insights into the mechanisms governing protein quality control and ERAD processes. Given its association with digestive disorders and inflammatory responses, ZG16B holds significance in gastrointestinal research. Investigating ZG16B provides potential applications in unraveling protein homeostasis, understanding ER stress responses, and exploring therapeutic strategies for conditions related to protein misfolding and degradation.