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The recombinant antibody against MYBBP1A was produced using a synthesized peptide derived from human MYBBP1A as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF.
The recombinant antibody against MYBBP1A was produced using a synthesized peptide derived from human MYBBP1A as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF.
$350.00
| Cat.No | ADC-56765A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | MYBBP1A | Target Synonyms | Myb-binding protein 1A, MYBBP1A, P160 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human MYBBP1A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BQG0 |
Uniprot Id
Q9BQG0
Target Species
Human
Target Name
MYBBP1A
Target Full Name
Myb-binding protein 1A
Target Function
May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter. Has a role in rRNA biogenesis together with PWP1.
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus, nucleolus.
Target Synonyms
P160; PAP2; Pol5; MYBBP1A
Target Background
This gene encodes a nucleolar transcriptional regulator that was first identified by its ability to bind specifically to the Myb proto-oncogene protein. The encoded protein is thought to play a role in many cellular processes including response to nucleolar stress, tumor suppression and synthesis of ribosomal DNA. Alternate splicing results in multiple transcript variants.
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