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STAG2 Recombinant Monoclonal Antibody

The recombinant antibody against STAG2 was produced using a synthesized peptide derived from human SA2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IF.

ADC-56918A

The recombinant antibody against STAG2 was produced using a synthesized peptide derived from human SA2 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IF.

$350.00

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Specifications


Cat.No ADC-56918A ClonalityMonoclonal
Target NameSTAG2Target SynonymsCohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2), SA2, STAG2
FormLiquidSpecies ReactivityHuman
IsotypeRabbit IgGStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline
Purification MethodAffinity-chromatography purifiedConjugateNon-conjugated
ApplicationELISA, IF, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionA synthesized peptide derived from human SA2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N3U4
Background Information
  • Uniprot Id

    Q8N3U4

  • Target Species

    Human

  • Target Name

    STAG2

  • Target Full Name

    Cohesin subunit SA-2

  • Target Function

    Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.

  • Target Subcellular Location

    Nucleus. Chromosome. Chromosome, centromere. Note=Associates with chromatin. Before prophase it is scattered along chromosome arms. During prophase, most of cohesin complexes dissociate from chromatin probably because of phosphorylation by PLK1, except at centromeres, where cohesin complexes remain. At anaphase, the RAD21 subunit of cohesin is cleaved, leading to the dissociation of the complex from chromosomes, allowing chromosome separation. In germ cells, cohesin complex dissociates from chromatin at prophase I, and may be replaced by a meiosis-specific cohesin complex.

  • Target Protein Families

    SCC3 family

  • Target Synonyms

    bA517O1.1; Cohesin Subunit SA 2; Cohesin subunit SA-2; DKFZp686P168; DKFZp781H1753; FLJ25871; SA 2; SA-2; SA2; SCC3 homolog 2; SCC3B; STAG 2; stag2; STAG2_HUMAN; Stromal antigen 2

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