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The recombinant antibody against TACR1 was produced using a synthesized peptide derived from human Neurokinin 1 Receptor as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The recombinant antibody against TACR1 was produced using a synthesized peptide derived from human Neurokinin 1 Receptor as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: THP-1 whole cell lysate, Hela whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, Ntera-2 whole cell lysate, Mouse Brain whole cell lysate | All lanes: TACR1 antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 47, 36 kDa | Observed band size: 50 kDa
| Cat.No | ADC-56857A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | TACR1 | Target Synonyms | NK1R TAC1R, Substance-P receptor (SPR) (NK-1 receptor) (NK-1R) (Tachykinin receptor 1), TACR1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human Neurokinin 1 Receptor | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P25103 |
Uniprot Id
P25103
Target Species
Human
Target Name
TACR1
Target Full Name
Substance-P receptor
Target Function
This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family
Target Research Area
Neuroscience
Target Synonyms
Neurokinin 1; Neurokinin 1 Receptor; NK 1 receptor; NK 1R; NK-1 receptor; NK-1R; NK1 receptor; NK1R; NK1R_HUMAN; NKIR; SPR; Substance P receptor; Substance-P receptor; TAC 1R; TAC1R; Tachykinin 1 receptor (substance P receptor neurokinin 1 receptor); Tachykinin receptor 1 (substance P receptor neurokinin 1 receptor); Tachykinin receptor 1; TACR1
Target Background
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.
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