Rabbit anti-Human Alpha Internexin Monoclonal Antibody

The antibody against Alpha Internexin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human Alpha Internexin (Q16352) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-14180A

Number

Cat.No	ADA-14180A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Alpha Internexin
Target Synonyms	NEF5; NF66; NF-66; TXBP-1; Alpha Internexin	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain, U-87MG	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-14180A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Alpha Internexin

Target Synonyms

NEF5; NF66; NF-66; TXBP-1; Alpha Internexin

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain, U-87MG

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Alpha Internexin (Q16352).	Target Species	Human
Immunogen Sequence	EVAGYQDSIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISGLNPLPNPSYLLPPRILSATTSKVSSTGLSLKKEE	Uniprot ID	Q16352

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 350-450 of human Alpha Internexin (Q16352).

Target Species

Human

Immunogen Sequence

EVAGYQDSIGQLENDLRNTKSEMARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTSGLSISGLNPLPNPSYLLPPRILSATTSKVSSTGLSLKKEE

Uniprot ID

Q16352

Background Information

Uniprot Id

Q16352
Target Species

Human
Target Name

INA
Target Full Name

Alpha-internexin
Target Function

Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NEFL to form the filamentous backbone to which NEFM and NEFH attach to form the cross-bridges. May also cooperate with the neuronal intermediate filament protein PRPH to form filamentous networks.
Target Protein Families

Intermediate filament family
Target Tissue Specificity

Found predominantly in adult CNS.
Target Synonyms

66 kDa neurofilament protein; AINX_HUMAN; Alpha Inx; Alpha-internexin; Alpha-Inx; INA; Internexin neuronal intermediate filament protein alpha ; MGC12702; NEF 5; NEF5; Neurofilament 5 (66kD); Neurofilament 5; Neurofilament 66; Neurofilament 66 tax binding protein ; Neurofilament-66; NF 66; NF-66; NF66 ; TXBP 1; TXBP1
Target Background

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene is a member of the intermediate filament family and is involved in the morphogenesis of neurons.

Rabbit anti-Human Alpha Internexin Monoclonal Antibody

Specifications

Immunogen Information

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