Rabbit anti-Human Periostin Monoclonal Antibody

The antibody against Periostin was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Periostin (NP_001129406.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-15855A

Number

Cat.No	ADA-15855A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Periostin
Target Synonyms	PN; OSF2; OSF-2; PDLPOSTN; Periostin	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	MCF7	Application	ELISA, WB

Cat.No

ADA-15855A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Periostin

Target Synonyms

PN; OSF2; OSF-2; PDLPOSTN; Periostin

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

MCF7

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Periostin (NP_001129406.1).	Target Species	Human
Immunogen Sequence	MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDH	Uniprot ID	Q15063

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Periostin (NP_001129406.1).

Target Species

Human

Immunogen Sequence

MIPFLPMFSLLLLLIVNPINANNHYDKILAHSRIRGRDQGPNVCALQQILGTKKKYFSTCKNWYKKSICGQKTTVLYECCPGYMRMEGMKGCPAVLPIDH

Uniprot ID

Q15063

Background Information

Uniprot Id

Q15063
Target Species

Human
Target Name

POSTN
Target Full Name

Periostin
Target Function

Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.
Target Subcellular Location

Golgi apparatus. Secreted. Secreted, extracellular space, extracellular matrix.
Target Tissue Specificity

Widely expressed with highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus, thyroid tissue and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of
Target Synonyms

PN; OSF2; OSF-2; PDLPOSTN; POSTN
Target Background

This gene encodes a secreted extracellular matrix protein that functions in tissue development and regeneration, including wound healing, and ventricular remodeling following myocardial infarction. The encoded protein binds to integrins to support adhesion and migration of epithelial cells. This protein plays a role in cancer stem cell maintenance and metastasis. Mice lacking this gene exhibit cardiac valve disease, and skeletal and dental defects. Alternative splicing results in multiple transcript variants encoding different isoforms.

Rabbit anti-Human Periostin Monoclonal Antibody

Specifications

Immunogen Information

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