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The antibody against CR2 was raised in mouse using the Synthesized peptide derived from human CD21 as the immunogen. This antibody exists as a non-conjugated isotype IgG1, Kappa. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody has been validated on ELISA, IHC.
The antibody against CR2 was raised in mouse using the Synthesized peptide derived from human CD21 as the immunogen. This antibody exists as a non-conjugated isotype IgG1, Kappa. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-56016A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Mouse | Target Name | CR2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG1, Kappa | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from human CD21 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P20023 |
Uniprot Id
P20023
Target Species
Human
Target Name
CR2
Target Full Name
Complement receptor type 2
Target Function
Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU. Participates in B lymphocytes activation.; (Microbial infection) Acts as a receptor for Epstein-Barr virus.
Target Involvement
Systemic lupus erythematosus 9 (SLEB9); Immunodeficiency, common variable, 7 (CVID7)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Receptors of complement activation (RCA) family
Target Tissue Specificity
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Target Synonyms
C3DR; CD 21; CD21; Complement C3d receptor 2; Complement C3d receptor; Complement component (3d/Epstein Barr virus) receptor 2; Complement receptor type 2; CR; Cr2; CR2_HUMAN; CVID7; EBV receptor; EBV-R; Epstein Barr virus receptor; Epstein-Barr virus receptor; EVBR; SLEB9
Target Background
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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