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The recombinant antibody against CR2 was produced using a synthesized peptide as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, IF, FC.
The recombinant antibody against CR2 was produced using a synthesized peptide as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, IF, FC.
$350.00
| Cat.No | ADC-56322A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | CR2 | Form | Liquid |
| Species Reactivity | Human | Isotype | Rabbit IgG |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB, FC |
| Storage | Upon receipt |
| Immunogen Description | A synthesized peptide | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P20023 |
Uniprot Id
P20023
Target Species
Human
Target Name
CR2
Target Full Name
Complement receptor type 2
Target Function
Receptor for complement C3, for the Epstein-Barr virus on human B-cells and T-cells and for HNRNPU. Participates in B lymphocytes activation.; (Microbial infection) Acts as a receptor for Epstein-Barr virus.
Target Involvement
Systemic lupus erythematosus 9 (SLEB9); Immunodeficiency, common variable, 7 (CVID7)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
Receptors of complement activation (RCA) family
Target Tissue Specificity
Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
Target Synonyms
C3DR; CD 21; CD21; Complement C3d receptor 2; Complement C3d receptor; Complement component (3d/Epstein Barr virus) receptor 2; Complement receptor type 2; CR; Cr2; CR2_HUMAN; CVID7; EBV receptor; EBV-R; Epstein Barr virus receptor; Epstein-Barr virus receptor; EVBR; SLEB9
Target Background
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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