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The recombinant antibody against GFAP was produced using a synthesized peptide derived from Human GFAP as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, FC.
The recombinant antibody against GFAP was produced using a synthesized peptide derived from Human GFAP as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, FC.
$350.00
| Cat.No | ADC-56514A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | gfap | Target Synonyms | GFAP, Glial fibrillary acidic protein (GFAP) |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human GFAP | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P14136 |
Uniprot Id
P14136
Target Species
Human
Target Name
GFAP
Target Full Name
Glial fibrillary acidic protein
Target Function
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Target Involvement
Alexander disease (ALXDRD)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Intermediate filament family
Target Tissue Specificity
Expressed in cells lacking fibronectin.
Target Research Area
Neuroscience
Target Synonyms
ALXDRD; GFAP
Target Background
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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