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The antibody against Human IgG4 (Fc) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 96-115 of Human IgG4 (Fc). (P01861) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against Human IgG4 (Fc) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 96-115 of Human IgG4 (Fc). (P01861) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-15156A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Human IgG4 (Fc) |
| Target Synonyms | IGHG4; Ig gamma-4 chain C region; Human IgG4 (Fc) | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa(Negative control), Human plasma | Application | ELISA, WB, IF/ICC |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 96-115 of Human IgG4 (Fc). (P01861). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | KRVESKYGPPCPSCPAPEFL | Uniprot ID | P01861 |
Uniprot Id
P01861
Target Species
Human
Target Name
IGHG4
Target Full Name
Immunoglobulin heavy constant gamma 4
Target Function
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen
Target Subcellular Location
Secreted. Cell membrane.
Target Synonyms
IGHG4; Immunoglobulin heavy constant gamma 4; Ig gamma-4 chain C region
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