Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against MGLL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MGLL as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against MGLL was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MGLL as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-15104A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Mgll |
| Target Synonyms | MGL; HUK5; MAGL; HU-K5; MGLL | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat heart, Mouse fat | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MGLL | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99685 |
Uniprot Id
Q99685
Target Species
Human
Target Name
MGLL
Target Full Name
Monoglyceride lipase
Target Function
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
Target Subcellular Location
Cytoplasm, cytosol. Membrane; Peripheral membrane protein.
Target Protein Families
AB hydrolase superfamily, Monoacylglycerol lipase family
Target Tissue Specificity
Detected in adipose tissue, lung, liver, kidney, brain and heart.
Target Research Area
Cardiovascular
Target Synonyms
EC 3.1.1.23; HU K5 ; HU-K5; HUK5 ; Lysophospholipase homolog; Lysophospholipase like; Lysophospholipase-like; MAGL; MGL; MGLL; MGLL_HUMAN; Monoacylglycerol lipase; Monoglyceride lipase
Target Background
This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
