Rabbit anti-Human Mras Monoclonal Antibody

The antibody against Mras was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 109-208 of human Mras (O14807) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13409A

Number

Cat.No	ADA-13409A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	MRAS
Target Synonyms	NS11; M-RAs; RRAS3; R-RAS3; Mras	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	C6, HeLa, Mouse kidney, Rat brain, Mouse brain, Mouse lung, SH-SY5Y	Application	ELISA, WB

Cat.No

ADA-13409A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

MRAS

Target Synonyms

NS11; M-RAs; RRAS3; R-RAS3; Mras

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

C6, HeLa, Mouse kidney, Rat brain, Mouse brain, Mouse lung, SH-SY5Y

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 109-208 of human Mras (O14807).	Target Species	Human
Immunogen Sequence	LILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKSQKKKKKTKWRGDRATGTHKLQCVIL	Uniprot ID	O14807

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 109-208 of human Mras (O14807).

Target Species

Human

Immunogen Sequence

LILRVKDRESFPMILVANKVDLMHLRKITREQGKEMATKHNIPYIETSAKDPPLNVDKAFHDLVRVIRQQIPEKSQKKKKKTKWRGDRATGTHKLQCVIL

Uniprot ID

O14807

Background Information

Uniprot Id

O14807
Target Species

Human
Target Name

MRAS
Target Full Name

Ras-related protein M-Ras
Target Function

Serves as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway.
Target Subcellular Location

Cell membrane; Lipid-anchor; Cytoplasmic side.
Target Protein Families

Small GTPase superfamily, Ras family
Target Tissue Specificity

Expression highly restricted to the brain and heart.
Target Research Area

Cancer
Target Synonyms

FLJ42964; M ras; M-ras; Mras; Muscle and microspikes Ras; Muscle RAS oncogene homolog; Muscle Ras oncogene homologue; Muscle Ras viral oncogene homolog; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; Ras-related protein M-Ras; Ras-related protein R-Ras3; RASM_HUMAN; Related Ras viral oncogene homolog 3; RRas3; XRas
Target Background

This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Rabbit anti-Human Mras Monoclonal Antibody

Specifications

Immunogen Information

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