Rabbit anti-Human Smad5 Monoclonal Antibody

The antibody against Smad5 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 200-300 of human Smad5 (Q99717) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ELISA.

ADA-13636A

Number

Cat.No	ADA-13636A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	SMAD5
Target Synonyms	DWFC; JV5-1; MADH5; Smad5	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	C2C12, K-562	Application	ELISA, WB, IP

Cat.No

ADA-13636A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

SMAD5

Target Synonyms

DWFC; JV5-1; MADH5; Smad5

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

C2C12, K-562

Application

ELISA, WB, IP

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Smad5 (Q99717).	Target Species	Human
Immunogen Sequence	STYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT	Uniprot ID	Q99717

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Smad5 (Q99717).

Target Species

Human

Immunogen Sequence

STYPNSPASSGPGSPFQLPADTPPPAYMPPDDQMGQDNSQPMDTSNNMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFT

Uniprot ID

Q99717

Background Information

Uniprot Id

Q99717
Target Species

Human
Target Name

SMAD5
Target Full Name

Mothers against decapentaplegic homolog 5
Target Function

Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD).
Target Subcellular Location

Cytoplasm. Nucleus. Note=Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4.
Target Protein Families

Dwarfin/SMAD family
Target Tissue Specificity

Ubiquitous.
Target Synonyms

DKFZp781C1895; DKFZp781O1323; Dwfc; hSmad5; JV5 1; JV5-1; MAD homolog 5; MAD, mothers against decapentaplegic homolog 5; MADH 5; MADH5; Mothers against decapentaplegic homolog 5; mothers against decapentaplegic, drosophila, homolog of, 5; Mothers against DPP homolog 5; MusMLP; SMA and MAD related protein 5; SMAD 5; SMAD family member 5; SMAD, mothers against DPP homolog 5; Smad5; SMAD5_HUMAN
Target Background

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human Smad5 Monoclonal Antibody

Specifications

Immunogen Information

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