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Rabbit anti-Human VSNL1/VILIP-1 Monoclonal Antibody

The antibody against VSNL1/VILIP-1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-191 of human VSNL1/VILIP-1 (NP_003376.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-14755A

The antibody against VSNL1/VILIP-1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 2-191 of human VSNL1/VILIP-1 (NP_003376.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-14755A ClonalityMonoclonal
Host SpeciesRabbitTarget NameVSNL1/VILIP-1
Target SynonymsHLP3; VILIP; HPCAL3; HUVISL1; VILIP-1; VSNL1/VILIP-1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, Rat lung, SH-SY5YApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 2-191 of human VSNL1/VILIP-1 (NP_003376.2).Target SpeciesHuman
Immunogen SequenceGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGDASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVEMLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPSIVLLLQCDIQKUniprot IDP62760
Background Information
  • Uniprot Id

    P62760

  • Target Species

    Human

  • Target Name

    VSNL1

  • Target Full Name

    Visinin-like protein 1

  • Target Function

    Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

  • Target Protein Families

    Recoverin family

  • Target Tissue Specificity

    Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    21 kDa CABP; Hippocalcin like protein 3; Hippocalcin-like protein 3; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL1; Neural visinin-like protein 1; Neural visinin-like type 1 protein; Neurocalcin alpha; NVL 1; NVL1; Nvp1; OZ1; Ratnvp1; VILIP; VILIP-1; Visinin; Visinin like 1; Visinin like protein 1; Visinin-like protein 1; VISL 1; VISL1; VISL1_HUMAN; VLP-1; Vnsl1; Vsnl1

  • Target Background

    This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

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