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MAOA Recombinant Monoclonal Antibody

The recombinant antibody against MAOA was produced using a synthesized peptide derived from human Monoamine Oxidase A as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF.

ADC-56755A

The recombinant antibody against MAOA was produced using a synthesized peptide derived from human Monoamine Oxidase A as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF.

$350.00

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Specifications


Cat.No ADC-56755A ClonalityMonoclonal
Target NameMAOATarget SynonymsMAOA; Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A
FormLiquidSpecies ReactivityHuman
IsotypeRabbit IgGStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline
Purification MethodAffinity-chromatography purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionA synthesized peptide derived from human Monoamine Oxidase ATarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP21397
Background Information
  • Uniprot Id

    P21397

  • Target Species

    Human

  • Target Name

    MAOA

  • Target Full Name

    Amine oxidase [flavin-containing] A

  • Target Function

    Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.

  • Target Involvement

    Brunner syndrome (BRNRS)

  • Target Subcellular Location

    Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side.

  • Target Protein Families

    Flavin monoamine oxidase family

  • Target Tissue Specificity

    Heart, liver, duodenum, blood vessels and kidney.

  • Target Synonyms

    MAOA; Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A

  • Target Background

    This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.

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