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NT5E Recombinant Monoclonal Antibody

The recombinant antibody against NT5E was produced using a synthesized peptide derived from human CD73 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC.

ADC-56976A

The recombinant antibody against NT5E was produced using a synthesized peptide derived from human CD73 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC.

$350.00

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Specifications


Cat.No ADC-56976A ClonalityMonoclonal
Target NameNT5ETarget Synonyms5'-nucleotidase (5'-NT) (EC 3.1.3.5) (Ecto-5'-nucleotidase) (CD antigen CD73), NT5 NTE, NT5E
FormLiquidSpecies ReactivityHuman
IsotypeRabbit IgGStorage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline
Purification MethodAffinity-chromatography purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionA synthesized peptide derived from human CD73Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP21589
Background Information
  • Uniprot Id

    P21589

  • Target Species

    Human

  • Target Name

    NT5E

  • Target Full Name

    5'-nucleotidase

  • Target Function

    Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.

  • Target Involvement

    Calcification of joints and arteries (CALJA)

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    5'-nucleotidase family

  • Target Synonyms

    NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA; CD73/NT5E

  • Target Background

    The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

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