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The recombinant antibody against PANX1 was produced using a synthesized peptide derived from Human PANX1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF, FC.
The recombinant antibody against PANX1 was produced using a synthesized peptide derived from Human PANX1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, IHC, IF, FC.
$350.00
| Cat.No | ADC-56540A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | PANX1 | Target Synonyms | MRS1, Pannexin-1, PANX1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human PANX1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96RD7 |
Uniprot Id
Q96RD7
Target Species
Human
Target Name
PANX1
Target Full Name
Pannexin-1
Target Function
Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Pannexin family
Target Tissue Specificity
Widely expressed. Highest expression is observed in oocytes and brain. Detected at very low levels in sperm cells.
Target Synonyms
PANX1; MRS1; UNQ2529/PRO6028; Pannexin-1
Target Background
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
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