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The antibody against P2Y12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 120-347 of mouse Recombinant protein of Mouse P2Y12 (Q9CPV9) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against P2Y12 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 120-347 of mouse Recombinant protein of Mouse P2Y12 (Q9CPV9) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-14513A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | P2Y12 |
| Target Synonyms | P2Y12; 2900079B22Rik; 4921504D23Rik | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | C6, Rat brain, Mouse brain, Mouse spinal cord | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 120-347 of mouse Recombinant protein of Mouse P2Y12 (Q9CPV9). | Target Species | Mouse |
|---|---|---|---|
| Uniprot ID | Q9CPV9 | Immunogen Sequence |
Uniprot Id
Q9CPV9
Target Synonyms
P2Y12; 2900079B22Rik; 4921504D23Rik
Target Background
Enables G protein-coupled ADP receptor activity and G protein-coupled adenosine receptor activity. Involved in several processes, including cellular response to ATP; regulation of microglial cell migration; and substrate-dependent cell migration, cell extension. Acts upstream of or within several processes, including adenylate cyclase-modulating G protein-coupled receptor signaling pathway; platelet activation; and positive regulation of ion transport. Located in cell body membrane and cell projection membrane. Is expressed in central nervous system and cerebral cortex. Used to study platelet-type bleeding disorder 8. Human ortholog(s) of this gene implicated in asthma; cerebrovascular disease; peripheral artery disease; platelet-type bleeding disorder 8; and type 2 diabetes mellitus. Orthologous to human P2RY12 (purinergic receptor P2Y12).
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