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The antibody against Hex was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human Hex (Q03014) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against Hex was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human Hex (Q03014) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-16231A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Hex |
| Target Synonyms | HEX; PRH; HMPH; PRHX; HOX11L-PEN; Hex | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Hep G2 | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Hex (Q03014). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | TLPSPNSSFTSLVSPYRTPVYEPTPIHPAFSHHSAAALAAAYGPGGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKRKGGQVRFSNDQTI | Uniprot ID | Q03014 |
Uniprot Id
Q03014
Target Species
Human
Target Name
HHEX
Target Full Name
Hematopoietically-expressed homeobox protein HHEX
Target Function
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. Activator of WNT-mediated transcription in conjunction with CTNNB1. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL. May play a role in hematopoietic differentiation.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Liver and promyelocytic leukemia cell line HL-60.
Target Synonyms
HEX; PRH; HMPH; PRHX; HOX11L-PEN; Hex
Target Background
This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
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