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The recombinant antibody against CARS was produced using a synthesized peptide derived from human CARS as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The recombinant antibody against CARS was produced using a synthesized peptide derived from human CARS as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
$350.00
Western Blot | Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate, Jurkat whole cell lysate | All lanes: CARS antibody at 1:500 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 86, 83, 95 kDa | Observed band size: 95 kDa
| Cat.No | ADC-56651A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | CARS | Target Synonyms | CARS, Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human CARS | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49589 |
Uniprot Id
P49589
Target Species
Human
Target Name
CARS1
Target Full Name
Cysteine--tRNA ligase, cytoplasmic
Target Function
Catalyzes the ATP-dependent ligation of cysteine to tRNA(Cys).
Target Involvement
A chromosomal aberration involving CARS is associated with inflammatory myofibroblastic tumors (IMTs). Translocation t(2;11)(p23;p15) with ALK.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Class-I aminoacyl-tRNA synthetase family
Target Synonyms
Cysteine tRNA ligase; Cars; CysRS; Cysteine--tRNA ligase; Cysteinyl tRNA synthetase, cytoplasmic; Cysteinyl-tRNA synthetase; cytoplasmic; MGC:11246; SYCC_HUMAN
Target Background
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.
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