Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against CD1c was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-298 of human CD1c (NP_001756.2?) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on FC, ELISA.
The antibody against CD1c was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-298 of human CD1c (NP_001756.2?) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on FC, ELISA.
Flow cytometry: 1X10^6 K-562 cells (negative control, left)?and MOLT-4 cells (right) were surface-stained with CD1c Rabbit mAb or PE Rabbit IgG isotype control, followed by PE conjugated goat anti-rabbit pAb staining. Non-fluorescently stained cells were used as blank control (red line).
| Cat.No | ADA-13333A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD1C |
| Target Synonyms | R7; CD1; CD1A; BDCA1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, FC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 19-298 of human CD1c (NP_001756.2?). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P29017 | Immunogen Sequence |
Uniprot Id
P29017
Target Species
Human
Target Name
CD1C
Target Full Name
T-cell surface glycoprotein CD1c
Target Function
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome.
Target Tissue Specificity
Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
Target Research Area
Immunology
Target Synonyms
BDCA1; CD1; CD1A; CD1c; CD1c antigen; CD1C antigen c polypeptide; CD1c molecule; CD1C_HUMAN; Cortical thymocyte antigen CD1C; Differentiation antigen CD1 alpha 3; R7; T cell surface glycoprotein CD1c; T-cell surface glycoprotein CD1c
Target Background
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
