Rabbit anti-Human CTBP2 Monoclonal Antibody

The antibody against CTBP2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 346-445 of human CTBP2 (P56545) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, IP, ELISA.

ADA-14463A

Number

Cat.No	ADA-14463A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	CTBP2
Target Synonyms	CTBP2; C-terminal-binding protein 2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, NIH/3T3, Rat testis	Application	ELISA, WB, IF/ICC, IHC-P, IP

Cat.No

ADA-14463A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

CTBP2

Target Synonyms

CTBP2; C-terminal-binding protein 2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, NIH/3T3, Rat testis

Application

ELISA, WB, IF/ICC, IHC-P, IP

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 346-445 of human CTBP2 (P56545).	Target Species	Human
Immunogen Sequence	TGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ	Uniprot ID	P56545

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 346-445 of human CTBP2 (P56545).

Target Species

Human

Immunogen Sequence

TGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVAPGGLPAAMEGIIPGGIPVTHNLPTVAHPSQAPSPNQPTKHGDNREHPNEQ

Uniprot ID

P56545

Background Information

Uniprot Id

P56545
Target Species

Human
Target Name

CTBP2
Target Full Name

C-terminal-binding protein 2
Target Function

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation.; Isoform 2 probably acts as a scaffold for specialized synapses.
Target Subcellular Location

Nucleus. Cell junction, synapse.
Target Protein Families

D-isomer specific 2-hydroxyacid dehydrogenase family
Target Tissue Specificity

Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.
Target Synonyms

C terminal binding protein 2; C-terminal-binding protein 2; CtBP2; CTBP2_HUMAN; ribeye
Target Background

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.

Rabbit anti-Human CTBP2 Monoclonal Antibody

Specifications

Immunogen Information

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