Rabbit anti-Human Galactosidase alpha (GLA) Monoclonal Antibody

The antibody against Galactosidase alpha (GLA) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 50-150 of human Galactosidase alpha (GLA) (GLA) (P06280) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13939A

Number

Cat.No	ADA-13939A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Galactosidase alpha (GLA)
Target Synonyms	GALA; Galactosidase alpha (GLA)	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain, Raji	Application	ELISA, WB

Cat.No

ADA-13939A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Galactosidase alpha (GLA)

Target Synonyms

GALA; Galactosidase alpha (GLA)

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain, Raji

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Galactosidase alpha (GLA) (GLA) (P06280).	Target Species	Human
Immunogen Sequence	FMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFG	Uniprot ID	P06280

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Galactosidase alpha (GLA) (GLA) (P06280).

Target Species

Human

Immunogen Sequence

FMCNLDCQEEPDSCISEKLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSEGRLQADPQRFPHGIRQLANYVHSKGLKLGIYADVGNKTCAGFPGSFG

Uniprot ID

P06280

Background Information

Uniprot Id

P06280
Target Species

Human
Target Name

GLA
Target Full Name

Alpha-galactosidase A
Target Function

Catalyzes the hydrolysis of glycosphingolipids and participates in their degradation in the lysosome.
Target Involvement

Fabry disease (FD)
Target Subcellular Location

Lysosome.
Target Protein Families

Glycosyl hydrolase 27 family
Target Research Area

Cardiovascular
Target Synonyms

AGAL_HUMAN; Agalsidase alfa; Alpha D galactosidase A; Alpha D galactoside galactohydrolase 1; Alpha D galactoside galactohydrolase; Alpha gal A; Alpha galactosidase A; Alpha-D-galactosidase A; Alpha-D-galactoside galactohydrolase; Alpha-galactosidase A; GALA; Galactosidase; alpha; GLA; GLA protein; Melibiase
Target Background

This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

Rabbit anti-Human Galactosidase alpha (GLA) Monoclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human Galactosidase alpha (GLA) Monoclonal Antibody Now

Related Products